Clinical Approach to The Diagnosis of Hereditary and Acquired Neuromuscular Diseases

Abstract

Progressive groups of neuromuscular diseases (NMDs), including hereditary and acquired forms, are heterogeneous pathologies affecting lower motoneurons, resulting in multisystem changes and complicating diagnosis. Diseases such as myotonic dystrophy, myasthenia gravis, and spinal muscular atrophy are characterised by a variety of symptoms and require a comprehensive approach to diagnosis, including molecular genetic development and neuroimaging. In Tajikistan, the increased mortality rate of NMDs may be related to hereditary predisposition and environmental factors, which necessitates the development of diagnostic and educational programs. The present study aims to investigate the incidence, risk factors, and diagnostic methods of NMDs in Tajikistan. The findings show that improved diagnosis and increased detection of the incidence of the disease allow to provide better medical care and improve the quality of life of patients.